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Monday, January 26

A blizzard warning goes into effect for our area this evening and Connecticut has issued a statewide travel ban starting at 9 p.m. The University is now closed as of 3 p.m. today and will be closed all day tomorrow, Tuesday, Jan. 27.  Day and evening classes are canceled through tomorrow. An updated advisory on the status of classes and operations for Wednesday will be posted Tuesday evening. During the time that the University is closed, the Commons, Subway, and Village Market will maintain regular hours for residential dining services and the Sports Center will be open for use by residential students only. Gengras Student Union and University Libraries will be closed.   snow closing guide

All Hartt Community Division activities through tomorrow are canceled.

current as of 3:05 p.m., Jan. 26, 2015

Yingcui Li, PhD

Assistant Professor

Biology Department

Bio Chem Building 160F

860.768.4533

yinli@hartford.edu


PhD   Temple University


Research Interests:

Yingcui Li's research is on genes and development. As a developmental biologist and cartilage biologist, her research has been focused on function of Hyaluronan, a large molecular made by cartilage cells, for limb and synovial joint development. Recently, she has developed transgenic mouse models for the genetic analysis of Hyaluronan function in Osteoarthritis. The general goal of her research is to provide insight into new targets and reveal new approaches for Osteoarthritis treatment, including novel drug target or gene therapy.

Yingcui Li's research has been supported by the Arthritis National Research Foundation and she has been awarded as an ANRF scholar. She is currently a member of the Society of Developmental Biology (SDB) and the American Society for Cell Biology (ASCB). She is also an invited member of the International Society for Hyaluronan Sciences (ISHAS).

Selected Peer Reviewed Publications:

Dyment N, Hagiwara Y, Mattews B, Li Y, Kalajzic I, Rowe D. 2014. Lineage tracing of progenitor cells that contribute to distinct regions of tendons during growth and natural healing. PLoS ONE, in Press.

Li Y, Fisher M, Shepard J, Iwamoto R, Dealy C. 2013. EGFR signals are negative regulators of chondrocyte maturation. Manuscript in Preparation.

Fisher M, Ferrari D, Li Y, Shepard JB, Patterson S, Anderson N, Dealy CN. 2012. The potential of human embryonic stem cells for articular cartilage repair and osteoarthritis: A review. Rheumatology Current Research. S3:1-10.

Liu Y, Wang L, Fatahi R, Kronenberg M, Kalajzic I, Rowe D, Li Y, Maye P. 2010. Isolation of murine bone marrow derived mesenchymal stem cells using Twist2 Cre transgenic mice. Bone. 47:916-925.

Matsumoto K,*, Li Y* (co-first authors), Jakuba C, Sugiyama Y, Sayo T, Okuno M, Dealy CN, Toole BP, Takeda J, Yamaguchi Y, Kosher RA. Conditional Inactivation of Has2 Reveals a Crucial Role for Hyaluronan in Skeletal Growth, Patterning, Chondrocyte Maturation, and Joint Formation in the Developing Limb. 2009. Development. 136(16):2825-35. 

 Li Y, Toole BP, Dealy CN, Kosher RA. Hyaluronan in Limb Morphogenesis. 2007. Developmental Biology. 305(2): 411-20. NOTE: Selected as a "Must Read" in Faculty of 1000 Biology.

Chin H, Fisher M, Li Y, Ferrari D, Wang C, Lichtler A, Dealy CN, Kosher RK. Studies on the role of Dlx5 in regulation of chondrocyte differentiation during endochondral ossification in the developing mouse limb. 2007. Development, Growth and Differentiation. 49(6): 515-521.

Fisher M, Li Y, Seghatoleslami MR, Dealy CN, Kosher RA. Heparan sulfate proteoglycans including syndecan-3 modulate BMP activity during limb cartilage differentiation. 2006. Matrix Biology. 25(1): 27-39.